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N‐acetylcysteine attenuates the development of cardiac fibrosis and remodeling in a mouse model of heart failure

Oxidative stress plays a central role in the pathogenesis of heart failure. We aimed to determine whether the antioxidant N‐acetylcysteine can attenuate cardiac fibrosis and remodeling in a mouse model of heart failure. Minipumps were implanted subcutaneously in wild‐type mice (n = 20) and mice with...

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Detalles Bibliográficos
Autores principales:	Giam, Beverly, Chu, Po‐Yin, Kuruppu, Sanjaya, Smith, A. Ian, Horlock, Duncan, Kiriazis, Helen, Du, Xiao‐Jun, Kaye, David M., Rajapakse, Niwanthi W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831326/ https://www.ncbi.nlm.nih.gov/pubmed/27081162 http://dx.doi.org/10.14814/phy2.12757

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