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Non‐neuronal, but atropine‐sensitive ileal contractile responses to short‐chain fatty acids: age‐dependent desensitization and restoration under inflammatory conditions in mice

Intestinal epithelial cells sense short‐chain fatty acids (SCFAs) to secrete non‐neuronal acetylcholine (ACh). However, the roles of luminal SCFAs and epithelial ACh under normal and pathological conditions remain unknown. We examined ileal contractile responses to SCFAs at different ages and their...

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Detalles Bibliográficos
Autores principales: Yajima, Masako, Kimura, Shunsuke, Karaki, Shinichiro, Nio‐Kobayashi, Junko, Tsuruta, Takeshi, Kuwahara, Atsukazu, Yajima, Takaji, Iwanaga, Toshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831327/
https://www.ncbi.nlm.nih.gov/pubmed/27053293
http://dx.doi.org/10.14814/phy2.12759