Systematic analysis of the kalimantacin assembly line NRPS module using an adapted targeted mutagenesis approach

Kalimantacin is an antimicrobial compound with strong antistaphylococcal activity that is produced by a hybrid trans‐acyltransferase polyketide synthase/nonribosomal peptide synthetase system in Pseudomonas fluorescens BCCM_ID9359. We here present a systematic analysis of the substrate specificity o...

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Detalles Bibliográficos
Autores principales: Uytterhoeven, Birgit, Appermans, Kenny, Song, Lijiang, Masschelein, Joleen, Lathouwers, Thomas, Michiels, Chris W., Lavigne, Rob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831472/
https://www.ncbi.nlm.nih.gov/pubmed/26666990
http://dx.doi.org/10.1002/mbo3.326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831472/
https://www.ncbi.nlm.nih.gov/pubmed/26666990
http://dx.doi.org/10.1002/mbo3.326

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