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Asenapine modulates nitric oxide release and calcium movements in cardiomyoblasts

OBJECTIVE: To examine the effects of asenapine on nitric oxide (NO) release and Ca(2+) transients in H9C2 cell line, which were either subjected to peroxidation or not. MATERIALS AND METHODS: H9C2 were treated with asenapine alone or in presence of intracellular kinase blockers, serotoninergic and d...

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Detalles Bibliográficos
Autores principales: Grossini, Elena, Gramaglia, Carla, Farruggio, Serena, Camillo, Lara, Mary, David, Vacca, Giovanni, Zeppegno, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831496/
https://www.ncbi.nlm.nih.gov/pubmed/27127388
http://dx.doi.org/10.4103/0976-500X.179358