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Conditional Knockout of Src Homology 2 Domain-containing Protein Tyrosine Phosphatase-2 in Myeloid Cells Attenuates Renal Fibrosis after Unilateral Ureter Obstruction

BACKGROUND: Src homology 2 domain-containing protein tyrosine phosphatase-2 (SHP-2) is a kind of intracellular protein tyrosine phosphatase. Studies have revealed its roles in various disease, however, whether SHP-2 involves in renal fibrosis remains unclear. The aim of this study was to explore the...

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Detalles Bibliográficos
Autores principales: Teng, Jing-Fei, Wang, Kai, Li, Yao, Qu, Fa-Jun, Yuan, Qing, Cui, Xin-Gang, Wang, Quan-Xing, Xu, Dan-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831547/
https://www.ncbi.nlm.nih.gov/pubmed/25947403
http://dx.doi.org/10.4103/0366-6999.156121