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Mechanistic Insight of Bivalent Compound 21MO as Potential Neuroprotectant for Alzheimer’s Disease

We have recently developed a bivalent strategy to provide novel compounds that potentially target multiple risk factors involved in the development of Alzheimer’s disease (AD). Our previous studies employing a bivalent compound with a shorter spacer (17MN) implicated that this compound can localize...

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Detalles Bibliográficos
Autores principales: Saathoff, John M., Liu, Kai, Chojnacki, Jeremy E., He, Liu, Chen, Qun, Lesnefsky, Edward J., Zhang, Shijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831581/
https://www.ncbi.nlm.nih.gov/pubmed/27023508
http://dx.doi.org/10.3390/molecules21040412