Cargando…

X-ray Crystallographic Structures of a Trimer, Dodecamer, and Annular Pore Formed by an Aβ(17–36) β-Hairpin

[Image: see text] High-resolution structures of oligomers formed by the β-amyloid peptide Aβ are needed to understand the molecular basis of Alzheimer’s disease and develop therapies. This paper presents the X-ray crystallographic structures of oligomers formed by a 20-residue peptide segment derive...

Descripción completa

Detalles Bibliográficos
Autores principales: Kreutzer, Adam G., Hamza, Imane L., Spencer, Ryan K., Nowick, James S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831588/
https://www.ncbi.nlm.nih.gov/pubmed/26967810
http://dx.doi.org/10.1021/jacs.6b01332