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Folate receptor-targeted liposomes loaded with a diacid metabolite of norcantharidin enhance antitumor potency for H22 hepatocellular carcinoma both in vitro and in vivo

The diacid metabolite of norcantharidin (DM-NCTD) is clinically effective against hepatocellular carcinoma (HCC), but is limited by its short half-life and high incidence of adverse effects at high doses. We developed a DM-NCTD-loaded, folic acid (FA)-modified, polyethylene glycolated (DM-NCTD/FA-PE...

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Detalles Bibliográficos
Autores principales: Liu, Min-Chen, Liu, Lin, Wang, Xia-Rong, Shuai, Wu-Ping, Hu, Ying, Han, Min, Gao, Jian-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831591/
https://www.ncbi.nlm.nih.gov/pubmed/27110110
http://dx.doi.org/10.2147/IJN.S96862