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Folate receptor-targeted liposomes loaded with a diacid metabolite of norcantharidin enhance antitumor potency for H22 hepatocellular carcinoma both in vitro and in vivo
The diacid metabolite of norcantharidin (DM-NCTD) is clinically effective against hepatocellular carcinoma (HCC), but is limited by its short half-life and high incidence of adverse effects at high doses. We developed a DM-NCTD-loaded, folic acid (FA)-modified, polyethylene glycolated (DM-NCTD/FA-PE...
Autores principales: | Liu, Min-Chen, Liu, Lin, Wang, Xia-Rong, Shuai, Wu-Ping, Hu, Ying, Han, Min, Gao, Jian-Qing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831591/ https://www.ncbi.nlm.nih.gov/pubmed/27110110 http://dx.doi.org/10.2147/IJN.S96862 |
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