Cargando…

Corticostriatal synaptic adaptations in Huntington’s disease

Huntington’s disease (HD) is a progressive neurodegenerative disorder that profoundly impairs corticostriatal information processing. While late stage pathology includes cell death, the appearance of motor symptoms parallels more subtle changes in neuronal function and synaptic integration. Because...

Descripción completa

Detalles Bibliográficos
Autores principales: Plotkin, Joshua L., Surmeier, D. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831704/
https://www.ncbi.nlm.nih.gov/pubmed/25700146
http://dx.doi.org/10.1016/j.conb.2015.01.020