Fetal Genotyping in Maternal Blood by Digital PCR: Towards NIPD of Monogenic Disorders Independently of Parental Origin

PURPOSE: To date, non-invasive prenatal diagnosis (NIPD) of monogenic disorders has been limited to cases with a paternal origin. This work shows a validation study of the Droplet Digital PCR (ddPCR) technology for analysis of both paternally and maternally inherited fetal alleles. For the purpose,...

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Detalles Bibliográficos
Autores principales: Perlado, Sara, Bustamante-Aragonés, Ana, Donas, Marta, Lorda-Sánchez, Isabel, Plaza, Javier, Rodríguez de Alba, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831728/
https://www.ncbi.nlm.nih.gov/pubmed/27078875
http://dx.doi.org/10.1371/journal.pone.0153258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831728/
https://www.ncbi.nlm.nih.gov/pubmed/27078875
http://dx.doi.org/10.1371/journal.pone.0153258

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