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The Proton-Sensing G-Protein Coupled Receptor GPR4 Promotes Angiogenesis in Head and Neck Cancer

Squamous cell carcinoma of the head and neck (SCCHN) is an aggressive disease with poor survival and is the sixth most common cancer worldwide. Gastroesophageal reflux is a common event in SCCHN patients. GPR4 is a proton-sensing G-protein coupled receptor, which can be activated by acidosis. The ob...

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Detalles Bibliográficos
Autores principales: Jing, Zhibin, Xu, Hongbo, Chen, Xiaohong, Zhong, Qi, Huang, Junwei, Zhang, Yang, Guo, Wei, Yang, Zheng, Ding, Shuo, Chen, Ping, Huang, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831743/
https://www.ncbi.nlm.nih.gov/pubmed/27078157
http://dx.doi.org/10.1371/journal.pone.0152789