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The Proton-Sensing G-Protein Coupled Receptor GPR4 Promotes Angiogenesis in Head and Neck Cancer
Squamous cell carcinoma of the head and neck (SCCHN) is an aggressive disease with poor survival and is the sixth most common cancer worldwide. Gastroesophageal reflux is a common event in SCCHN patients. GPR4 is a proton-sensing G-protein coupled receptor, which can be activated by acidosis. The ob...
Autores principales: | Jing, Zhibin, Xu, Hongbo, Chen, Xiaohong, Zhong, Qi, Huang, Junwei, Zhang, Yang, Guo, Wei, Yang, Zheng, Ding, Shuo, Chen, Ping, Huang, Zhigang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831743/ https://www.ncbi.nlm.nih.gov/pubmed/27078157 http://dx.doi.org/10.1371/journal.pone.0152789 |
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