Targeting HIV-1 Env gp140 to LOX-1 Elicits Immune Responses in Rhesus Macaques

Improved antigenicity against HIV-1 envelope (Env) protein is needed to elicit vaccine-induced protective immunity in humans. Here we describe the first tests in non-human primates (NHPs) of Env gp140 protein fused to a humanized anti-LOX-1 recombinant antibody for delivering Env directly to LOX-1-b...

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Detalles Bibliográficos
Autores principales: Zurawski, Gerard, Zurawski, Sandra, Flamar, Anne-Laure, Richert, Laura, Wagner, Ralf, Tomaras, Georgia D., Montefiori, David C., Roederer, Mario, Ferrari, Guido, Lacabaratz, Christine, Bonnabau, Henri, Klucar, Peter, Wang, Zhiqing, Foulds, Kathryn E., Kao, Shing-Fen, Yates, Nicole L., LaBranche, Celia, Jacobs, Bertram L., Kibler, Karen, Asbach, Benedikt, Kliche, Alexander, Salazar, Andres, Reed, Steve, Self, Steve, Gottardo, Raphael, Galmin, Lindsey, Weiss, Deborah, Cristillo, Anthony, Thiebaut, Rodolphe, Pantaleo, Giuseppe, Levy, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831750/
https://www.ncbi.nlm.nih.gov/pubmed/27077384
http://dx.doi.org/10.1371/journal.pone.0153484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831750/
https://www.ncbi.nlm.nih.gov/pubmed/27077384
http://dx.doi.org/10.1371/journal.pone.0153484

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