Retinoid X Receptor Agonists Upregulate Genes Responsible for the Biosynthesis of All-Trans-Retinoic Acid in Human Epidermis

UAB30 is an RXR selective agonist that has been shown to have potential cancer chemopreventive properties. Due to high efficacy and low toxicity, it is currently being evaluated in human Phase I clinical trials by the National Cancer Institute. While UAB30 shows promise as a low toxicity chemopreven...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Lizhi, Chaudhary, Sandeep C., Atigadda, Venkatram R., Belyaeva, Olga V., Harville, Steven R., Elmets, Craig A., Muccio, Donald D., Athar, Mohammad, Kedishvili, Natalia Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831765/
https://www.ncbi.nlm.nih.gov/pubmed/27078158
http://dx.doi.org/10.1371/journal.pone.0153556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831765/
https://www.ncbi.nlm.nih.gov/pubmed/27078158
http://dx.doi.org/10.1371/journal.pone.0153556

Ejemplares similares