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Sphingomyelinase D from Loxosceles laeta Venom Induces the Expression of MMP7 in Human Keratinocytes: Contribution to Dermonecrosis

Envenomation by Loxosceles spider is characterized by the development of dermonecrosis. In previous studies, we have demonstrated that increased expression/secretion of matrix metalloproteinases 2 and 9, induced by Loxosceles intermedia venom Class 2 SMases D (the main toxin in the spider venom), co...

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Detalles Bibliográficos
Autores principales: Corrêa, Mara A., Okamoto, Cinthya K., Gonçalves-de-Andrade, Rute M., van den Berg, Carmen W., Tambourgi, Denise V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831769/
https://www.ncbi.nlm.nih.gov/pubmed/27078876
http://dx.doi.org/10.1371/journal.pone.0153090