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Lineage Tracking for Probing Heritable Phenotypes at Single-Cell Resolution

Determining the phenotype and genotype of single cells is central to understand microbial evolution. DNA sequencing technologies allow the detection of mutants at high resolution, but similar approaches for phenotypic analyses are still lacking. We show that a drop-based millifluidic system enables...

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Detalles Bibliográficos
Autores principales: Cottinet, Denis, Condamine, Florence, Bremond, Nicolas, Griffiths, Andrew D., Rainey, Paul B., de Visser, J. Arjan G. M., Baudry, Jean, Bibette, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831777/
https://www.ncbi.nlm.nih.gov/pubmed/27077662
http://dx.doi.org/10.1371/journal.pone.0152395