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Lineage Tracking for Probing Heritable Phenotypes at Single-Cell Resolution
Determining the phenotype and genotype of single cells is central to understand microbial evolution. DNA sequencing technologies allow the detection of mutants at high resolution, but similar approaches for phenotypic analyses are still lacking. We show that a drop-based millifluidic system enables...
Autores principales: | Cottinet, Denis, Condamine, Florence, Bremond, Nicolas, Griffiths, Andrew D., Rainey, Paul B., de Visser, J. Arjan G. M., Baudry, Jean, Bibette, Jérôme |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831777/ https://www.ncbi.nlm.nih.gov/pubmed/27077662 http://dx.doi.org/10.1371/journal.pone.0152395 |
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