Progressive Axonal Degeneration of Nigrostriatal Dopaminergic Neurons in Calcium-Independent Phospholipase A(2)β Knockout Mice

Calcium-independent phospholipase A(2)β (iPLA(2)β, PLA2G6) is essential for the remodeling of membrane glycerophospholipids. Mutations in this gene are responsible for autosomal recessive, young onset, L-dopa-responsive parkinsonism (PARK14), suggesting a neurodegenerative condition in the nigrostri...

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Detalles Bibliográficos
Autores principales: Beck, Goichi, Shinzawa, Koei, Hayakawa, Hideki, Baba, Kousuke, Sumi-Akamaru, Hisae, Tsujimoto, Yoshihide, Mochizuki, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831782/
https://www.ncbi.nlm.nih.gov/pubmed/27078024
http://dx.doi.org/10.1371/journal.pone.0153789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831782/
https://www.ncbi.nlm.nih.gov/pubmed/27078024
http://dx.doi.org/10.1371/journal.pone.0153789

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