Cargando…
Progressive Axonal Degeneration of Nigrostriatal Dopaminergic Neurons in Calcium-Independent Phospholipase A(2)β Knockout Mice
Calcium-independent phospholipase A(2)β (iPLA(2)β, PLA2G6) is essential for the remodeling of membrane glycerophospholipids. Mutations in this gene are responsible for autosomal recessive, young onset, L-dopa-responsive parkinsonism (PARK14), suggesting a neurodegenerative condition in the nigrostri...
Autores principales: | Beck, Goichi, Shinzawa, Koei, Hayakawa, Hideki, Baba, Kousuke, Sumi-Akamaru, Hisae, Tsujimoto, Yoshihide, Mochizuki, Hideki |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831782/ https://www.ncbi.nlm.nih.gov/pubmed/27078024 http://dx.doi.org/10.1371/journal.pone.0153789 |
Ejemplares similares
-
Deficiency of Calcium-Independent Phospholipase A2 Beta Induces Brain Iron Accumulation through Upregulation of Divalent Metal Transporter 1
por: Beck, Goichi, et al.
Publicado: (2015) -
High expression of α-synuclein in damaged mitochondria with PLA2G6 dysfunction
por: Sumi-Akamaru, Hisae, et al.
Publicado: (2016) -
Tumefactive brain lesion with rapid cavity formation associated with anti-aquaporin-4 antibody
por: Uehara, Takuya, et al.
Publicado: (2016) -
PLA(2) activity is required for nuclear shrinkage in caspase-independent cell death
por: Shinzawa, Koei, et al.
Publicado: (2003) -
Astrocytes and retrograde degeneration of nigrostriatal dopaminergic neurons in Parkinson’s disease: removing axonal debris
por: Morales, Ingrid, et al.
Publicado: (2021)