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Ammonia Induces Autophagy through Dopamine Receptor D3 and MTOR

Hyperammonemia is frequently seen in tumor microenvironments as well as in liver diseases where it can lead to severe brain damage or death. Ammonia induces autophagy, a mechanism that tumor cells may use to protect themselves from external stresses. However, how cells sense ammonia has been unclear...

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Detalles Bibliográficos
Autores principales: Li, Zhiyuan, Ji, Xinmiao, Wang, Wenchao, Liu, Juanjuan, Liang, Xiaofei, Wu, Hong, Liu, Jing, Eggert, Ulrike S., Liu, Qingsong, Zhang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831814/
https://www.ncbi.nlm.nih.gov/pubmed/27077655
http://dx.doi.org/10.1371/journal.pone.0153526