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Ups and Downs of Poised RNA Polymerase II in B-Cells

Recent genome-wide analyses have uncovered a high accumulation of RNA polymerase II (Pol II) at the 5′ end of genes. This elevated Pol II presence at promoters, referred to here as Poll II poising, is mainly (but not exclusively) attributed to temporal pausing of transcription during early elongatio...

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Detalles Bibliográficos
Autores principales: Dao, Phuong, Wojtowicz, Damian, Nelson, Steevenson, Levens, David, Przytycka, Teresa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831825/
https://www.ncbi.nlm.nih.gov/pubmed/27078128
http://dx.doi.org/10.1371/journal.pcbi.1004821