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Computational Reconstruction of NFκB Pathway Interaction Mechanisms during Prostate Cancer

Molecular research in cancer is one of the largest areas of bioinformatic investigation, but it remains a challenge to understand biomolecular mechanisms in cancer-related pathways from high-throughput genomic data. This includes the Nuclear-factor-kappa-B (NFκB) pathway, which is central to the inf...

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Detalles Bibliográficos
Autores principales: Börnigen, Daniela, Tyekucheva, Svitlana, Wang, Xiaodong, Rider, Jennifer R., Lee, Gwo-Shu, Mucci, Lorelei A., Sweeney, Christopher, Huttenhower, Curtis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831844/
https://www.ncbi.nlm.nih.gov/pubmed/27078000
http://dx.doi.org/10.1371/journal.pcbi.1004820