Unique spatiotemporal activation pattern of Cdc42 by Gef1 and Scd1 promotes different events during cytokinesis

The Rho-family GTPase Cdc42 regulates cell polarity and localizes to the cell division site. Cdc42 is activated by guanine nucleotide exchange factors (GEFs). We report that Cdc42 promotes cytokinesis via a unique spatiotemporal activation pattern due to the distinct action of its GEFs, Gef1 and Scd...

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Detalles Bibliográficos
Autores principales: Wei, Bin, Hercyk, Brian S., Mattson, Nicholas, Mohammadi, Ahmad, Rich, Julie, DeBruyne, Erica, Clark, Mikayla M., Das, Maitreyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831878/
https://www.ncbi.nlm.nih.gov/pubmed/26941334
http://dx.doi.org/10.1091/mbc.E15-10-0700

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831878/
https://www.ncbi.nlm.nih.gov/pubmed/26941334
http://dx.doi.org/10.1091/mbc.E15-10-0700

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