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Mechanical confinement triggers glioma linear migration dependent on formin FHOD3

Glioblastomas are extremely aggressive brain tumors with highly invasive properties. Brain linear tracks such as blood vessel walls constitute their main invasive routes. Here we analyze rat C6 and patient-derived glioma cell motility in vitro using micropatterned linear tracks to mimic blood vessel...

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Detalles Bibliográficos
Autores principales: Monzo, Pascale, Chong, Yuk Kien, Guetta-Terrier, Charlotte, Krishnasamy, Anitha, Sathe, Sharvari R., Yim, Evelyn K. F., Ng, Wai Hoe, Ang, Beng Ti, Tang, Carol, Ladoux, Benoit, Gauthier, Nils C., Sheetz, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831879/
https://www.ncbi.nlm.nih.gov/pubmed/26912794
http://dx.doi.org/10.1091/mbc.E15-08-0565