Cargando…

Unique epigenetic influence of H2AX phosphorylation and H3K56 acetylation on normal stem cell radioresponses

Normal tissue injury resulting from cancer radiotherapy is often associated with diminished regenerative capacity. We examined the relative radiosensitivity of normal stem cell populations compared with non–stem cells within several radiosensitive tissue niches and culture models. We found that thes...

Descripción completa

Detalles Bibliográficos
Autores principales: Jacobs, Keith M., Misri, Sandeep, Meyer, Barbara, Raj, Suyash, Zobel, Cheri L., Sleckman, Barry P., Hallahan, Dennis E., Sharma, Girdhar G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831886/
https://www.ncbi.nlm.nih.gov/pubmed/26941327
http://dx.doi.org/10.1091/mbc.E16-01-0017