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Sorting nexin 27 couples PTHR trafficking to retromer for signal regulation in osteoblasts during bone growth

The parathyroid hormone 1 receptor (PTHR) is central to the process of bone formation and remodeling. PTHR signaling requires receptor internalization into endosomes, which is then terminated by recycling or degradation. Here we show that sorting nexin 27 (SNX27) functions as an adaptor that couples...

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Detalles Bibliográficos
Autores principales: Chan, Audrey S. M., Clairfeuille, Thomas, Landao-Bassonga, Euphemie, Kinna, Genevieve, Ng, Pei Ying, Loo, Li Shen, Cheng, Tak Sum, Zheng, Minghao, Hong, Wanjin, Teasdale, Rohan D., Collins, Brett M., Pavlos, Nathan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831889/
https://www.ncbi.nlm.nih.gov/pubmed/26912788
http://dx.doi.org/10.1091/mbc.E15-12-0851