Achieving high signal-to-noise in cell regulatory systems: Spatial organization of multiprotein transmembrane assemblies of FGFR and MET receptors

How is information communicated both within and between cells of living systems with high signal to noise? We discuss transmembrane signaling models involving two receptor tyrosine kinases: the fibroblast growth factor receptor (FGFR) and the MET receptor. We suggest that simple dimerization models...

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Detalles Bibliográficos
Autores principales: Blaszczyk, Michal, Harmer, Nicholas J., Chirgadze, Dimitri Y., Ascher, David B., Blundell, Tom L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832006/
https://www.ncbi.nlm.nih.gov/pubmed/25957048
http://dx.doi.org/10.1016/j.pbiomolbio.2015.04.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832006/
https://www.ncbi.nlm.nih.gov/pubmed/25957048
http://dx.doi.org/10.1016/j.pbiomolbio.2015.04.007

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