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Tripartite containing motif 32 modulates proliferation of human neural precursor cells in HIV-1 neurodegeneration

In addition to glial cells, HIV-1 infection occurs in multipotent human neural precursor cells (hNPCs) and induces quiescence in NPCs. HIV-1 infection of the brain alters hNPC stemness, leading to perturbed endogenous neurorestoration of the CNS following brain damage by HIV-1, compounding the sever...

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Detalles Bibliográficos
Autores principales: Fatima, M, Kumari, R, Schwamborn, J C, Mahadevan, A, Shankar, S K, Raja, R, Seth, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832097/
https://www.ncbi.nlm.nih.gov/pubmed/26586575
http://dx.doi.org/10.1038/cdd.2015.138