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Onto better TRAILs for cancer treatment

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL), also known as Apo-2 ligand (Apo2L), is a member of the TNF cytokine superfamily. By cross-linking TRAIL-Receptor (TRAIL-R) 1 or TRAIL-R2, also known as death receptors 4 and 5 (DR4 and DR5), TRAIL has the capability to induce apo...

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Detalles Bibliográficos
Autores principales: de Miguel, D, Lemke, J, Anel, A, Walczak, H, Martinez-Lostao, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832109/
https://www.ncbi.nlm.nih.gov/pubmed/26943322
http://dx.doi.org/10.1038/cdd.2015.174