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Onto better TRAILs for cancer treatment
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL), also known as Apo-2 ligand (Apo2L), is a member of the TNF cytokine superfamily. By cross-linking TRAIL-Receptor (TRAIL-R) 1 or TRAIL-R2, also known as death receptors 4 and 5 (DR4 and DR5), TRAIL has the capability to induce apo...
Autores principales: | de Miguel, D, Lemke, J, Anel, A, Walczak, H, Martinez-Lostao, L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832109/ https://www.ncbi.nlm.nih.gov/pubmed/26943322 http://dx.doi.org/10.1038/cdd.2015.174 |
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