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Cancer therapy in the necroptosis era

Necroptosis is a caspase-independent form of regulated cell death executed by the receptor-interacting protein kinase 1 (RIP1), RIP3, and mixed lineage kinase domain-like protein (MLKL). Recently, necroptosis-based cancer therapy has been proposed to be a novel strategy for antitumor treatment. Howe...

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Detalles Bibliográficos
Autores principales: Su, Z, Yang, Z, Xie, L, DeWitt, J P, Chen, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832112/
https://www.ncbi.nlm.nih.gov/pubmed/26915291
http://dx.doi.org/10.1038/cdd.2016.8