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Prolonged activation of human islet cannabinoid receptors in vitro induces adaptation but not dysfunction

BACKGROUND: Although in vivo studies have implicated endocannabinoids in metabolic dysfunction, little is known about direct, chronic activation of the endocannabinoid system (ECS) in human islets. Therefore, this study investigated the effects of prolonged exposure to cannabinoid agonists on human...

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Detalles Bibliográficos
Autores principales: Vilches-Flores, Alonso, Franklin, Zara, Hauge-Evans, Astrid C., Liu, Bo, Huang, Guo C., Choudhary, Pratik, Jones, Peter M., Persaud, Shanta J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832123/
https://www.ncbi.nlm.nih.gov/pubmed/27114924
http://dx.doi.org/10.1016/j.bbacli.2016.03.009