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Prolonged activation of human islet cannabinoid receptors in vitro induces adaptation but not dysfunction
BACKGROUND: Although in vivo studies have implicated endocannabinoids in metabolic dysfunction, little is known about direct, chronic activation of the endocannabinoid system (ECS) in human islets. Therefore, this study investigated the effects of prolonged exposure to cannabinoid agonists on human...
Autores principales: | Vilches-Flores, Alonso, Franklin, Zara, Hauge-Evans, Astrid C., Liu, Bo, Huang, Guo C., Choudhary, Pratik, Jones, Peter M., Persaud, Shanta J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832123/ https://www.ncbi.nlm.nih.gov/pubmed/27114924 http://dx.doi.org/10.1016/j.bbacli.2016.03.009 |
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