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Blood metabolomics analysis identifies abnormalities in the citric acid cycle, urea cycle, and amino acid metabolism in bipolar disorder

BACKGROUND: Bipolar disorder (BD) is a severe and debilitating psychiatric disorder. However, the precise biological basis remains unknown, hampering the search for novel biomarkers. We performed a metabolomics analysis to discover novel peripheral biomarkers for BD. METHODS: We quantified serum lev...

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Detalles Bibliográficos
Autores principales: Yoshimi, Noriko, Futamura, Takashi, Kakumoto, Keiji, Salehi, Alireza M., Sellgren, Carl M., Holmén-Larsson, Jessica, Jakobsson, Joel, Pålsson, Erik, Landén, Mikael, Hashimoto, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832124/
https://www.ncbi.nlm.nih.gov/pubmed/27114925
http://dx.doi.org/10.1016/j.bbacli.2016.03.008