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Recombinant soluble gp130 protein reduces DEN-induced primary hepatocellular carcinoma in mice

IL-6 (interleukin 6) plays an important role in the development and growth of hepatocellular carcinoma (HCC) via both classic signaling and trans-signaling pathways. Soluble gp130 (sgp130) is known to be a natural inhibitor of the trans-signaling pathway. In the present study, our goal was to invest...

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Detalles Bibliográficos
Autores principales: Hong, Jing, Wang, Hang, Shen, Guoying, Lin, Da, Lin, Yanxue, Ye, Nanhui, Guo, Yashan, Li, Qiaoling, Deng, Chengjun, Meng, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832142/
https://www.ncbi.nlm.nih.gov/pubmed/27080032
http://dx.doi.org/10.1038/srep24397