PFKFB3 Control of Cancer Growth by Responding to Circadian Clock Outputs

Circadian clock dysregulation promotes cancer growth. Here we show that PFKFB3, the gene that encodes for inducible 6-phosphofructo-2-kinase as an essential supporting enzyme of cancer cell survival through stimulating glycolysis, mediates circadian control of carcinogenesis. In patients with tongue...

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Detalles Bibliográficos
Autores principales: Chen, Lili, Zhao, Jiajia, Tang, Qingming, Li, Honggui, Zhang, Chenguang, Yu, Ran, Zhao, Yan, Huo, Yuqing, Wu, Chaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832144/
https://www.ncbi.nlm.nih.gov/pubmed/27079271
http://dx.doi.org/10.1038/srep24324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832144/
https://www.ncbi.nlm.nih.gov/pubmed/27079271
http://dx.doi.org/10.1038/srep24324

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