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PFKFB3 Control of Cancer Growth by Responding to Circadian Clock Outputs
Circadian clock dysregulation promotes cancer growth. Here we show that PFKFB3, the gene that encodes for inducible 6-phosphofructo-2-kinase as an essential supporting enzyme of cancer cell survival through stimulating glycolysis, mediates circadian control of carcinogenesis. In patients with tongue...
Autores principales: | Chen, Lili, Zhao, Jiajia, Tang, Qingming, Li, Honggui, Zhang, Chenguang, Yu, Ran, Zhao, Yan, Huo, Yuqing, Wu, Chaodong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832144/ https://www.ncbi.nlm.nih.gov/pubmed/27079271 http://dx.doi.org/10.1038/srep24324 |
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