Cargando…

Frequent mechanical stress suppresses proliferation of mesenchymal stem cells from human bone marrow without loss of multipotency

Mounting evidence indicated that human mesenchymal stem cells (hMSCs) are responsive not only to biochemical but also to physical cues, such as substrate topography and stiffness. To simulate the dynamic structures of extracellular environments of the marrow in vivo, we designed a novel surrogate su...

Descripción completa

Detalles Bibliográficos
Autores principales: Frank, Viktoria, Kaufmann, Stefan, Wright, Rebecca, Horn, Patrick, Yoshikawa, Hiroshi Y., Wuchter, Patrick, Madsen, Jeppe, Lewis, Andrew L., Armes, Steven P., Ho, Anthony D., Tanaka, Motomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832181/
https://www.ncbi.nlm.nih.gov/pubmed/27080570
http://dx.doi.org/10.1038/srep24264