Mycobacteria-responsive sonic hedgehog signaling mediates programmed death-ligand 1- and prostaglandin E(2)-induced regulatory T cell expansion

CD4(+)CD25(+)FoxP3(+) regulatory T cells (Tregs) are exploited by mycobacteria to subvert the protective host immune responses. The Treg expansion in the periphery requires signaling by professional antigen presenting cells and in particularly dendritic cells (DC). However, precise molecular mechani...

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Detalles Bibliográficos
Autores principales: Holla, Sahana, Stephen-Victor, Emmanuel, Prakhar, Praveen, Sharma, Meenu, Saha, Chaitrali, Udupa, Vibha, Kaveri, Srinivas V., Bayry, Jagadeesh, Balaji, Kithiganahalli Narayanaswamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832185/
https://www.ncbi.nlm.nih.gov/pubmed/27080341
http://dx.doi.org/10.1038/srep24193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832185/
https://www.ncbi.nlm.nih.gov/pubmed/27080341
http://dx.doi.org/10.1038/srep24193

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