Structural basis of DNA sequence recognition by the response regulator PhoP in Mycobacterium tuberculosis

The transcriptional regulator PhoP is an essential virulence factor in Mycobacterium tuberculosis, and it presents a target for the development of new anti-tuberculosis drugs and attenuated tuberculosis vaccine strains. PhoP binds to DNA as a highly cooperative dimer by recognizing direct repeats of...

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Detalles Bibliográficos
Autores principales: He, Xiaoyuan, Wang, Liqin, Wang, Shuishu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832192/
https://www.ncbi.nlm.nih.gov/pubmed/27079268
http://dx.doi.org/10.1038/srep24442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832192/
https://www.ncbi.nlm.nih.gov/pubmed/27079268
http://dx.doi.org/10.1038/srep24442

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