MiR-299-5p regulates apoptosis through autophagy in neurons and ameliorates cognitive capacity in APPswe/PS1dE9 mice

Abnormalities of autophagy can result in neurodegenerative disorders such as Alzheimer’s disease (AD). Nevertheless, the regulatory mechanisms of autophagy in AD are not well understood. Here, we describe our findings that microRNA (miR)-299-5p functions as an autophagy inhibitor by suppressing Atg5...

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Detalles Bibliográficos
Autores principales: Zhang, Yueqi, Liu, Chengeng, Wang, Jinling, Li, Qiliang, Ping, Hong, Gao, Shichao, Wang, Peichang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832239/
https://www.ncbi.nlm.nih.gov/pubmed/27080144
http://dx.doi.org/10.1038/srep24566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832239/
https://www.ncbi.nlm.nih.gov/pubmed/27080144
http://dx.doi.org/10.1038/srep24566

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