The Parkinson Disease gene SNCA: Evolutionary and structural insights with pathological implication

After Alzheimer, Parkinson’s disease (PD) is the second most common neurodegenerative disorder. Alpha synuclein (SNCA) is deemed as a major component of Lewy bodies, a neuropathological feature of PD. Five point mutations in SNCA have been reported so far, responsible for autosomal dominant PD. This...

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Detalles Bibliográficos
Autores principales: Siddiqui, Irum Javaid, Pervaiz, Nashaiman, Abbasi, Amir Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832246/
https://www.ncbi.nlm.nih.gov/pubmed/27080380
http://dx.doi.org/10.1038/srep24475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832246/
https://www.ncbi.nlm.nih.gov/pubmed/27080380
http://dx.doi.org/10.1038/srep24475

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