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Titin stiffness modifies the force-generating region of muscle sarcomeres

The contractile units of striated muscle, the sarcomeres, comprise the thick (myosin) and thin (actin) filaments mediating active contraction and the titin filaments determining “passive” elasticity. We hypothesized that titin may be more active in muscle contraction by directly modulating thick-fil...

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Detalles Bibliográficos
Autores principales: Li, Yong, Lang, Patrick, Linke, Wolfgang A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832248/
https://www.ncbi.nlm.nih.gov/pubmed/27079135
http://dx.doi.org/10.1038/srep24492