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Titin stiffness modifies the force-generating region of muscle sarcomeres
The contractile units of striated muscle, the sarcomeres, comprise the thick (myosin) and thin (actin) filaments mediating active contraction and the titin filaments determining “passive” elasticity. We hypothesized that titin may be more active in muscle contraction by directly modulating thick-fil...
Autores principales: | Li, Yong, Lang, Patrick, Linke, Wolfgang A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832248/ https://www.ncbi.nlm.nih.gov/pubmed/27079135 http://dx.doi.org/10.1038/srep24492 |
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