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Integrative Phosphoproteomics Links IL-23R Signaling with Metabolic Adaptation in Lymphocytes

Interleukin (IL)-23 mediated signal transduction represents a major molecular mechanism underlying the pathology of inflammatory bowel disease, Crohn’s disease and ulcerative colitis. In addition, emerging evidence supports the role of IL-23-driven Th17 cells in inflammation. Components of the IL-23...

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Detalles Bibliográficos
Autores principales: Lochmatter, Corinne, Fischer, Roman, Charles, Philip D., Yu, Zhanru, Powrie, Fiona, Kessler, Benedikt M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832251/
https://www.ncbi.nlm.nih.gov/pubmed/27080861
http://dx.doi.org/10.1038/srep24491