In vitro selection of miltefosine resistance in promastigotes of Leishmania donovani from Nepal: genomic and metabolomic characterization

In this study, we followed the genomic, lipidomic and metabolomic changes associated with the selection of miltefosine (MIL) resistance in two clinically derived Leishmania donovani strains with different inherent resistance to antimonial drugs (antimony sensitive strain Sb‐S; and antimony resistant...

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Detalles Bibliográficos
Autores principales: Shaw, C. D., Lonchamp, J., Downing, T., Imamura, H., Freeman, T. M., Cotton, J. A., Sanders, M., Blackburn, G., Dujardin, J. C., Rijal, S., Khanal, B., Illingworth, C. J. R., Coombs, G. H., Carter, K. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832254/
https://www.ncbi.nlm.nih.gov/pubmed/26713880
http://dx.doi.org/10.1111/mmi.13291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832254/
https://www.ncbi.nlm.nih.gov/pubmed/26713880
http://dx.doi.org/10.1111/mmi.13291

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