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Calcitonin Gene‐Related Peptide–Expressing Sensory Neurons and Spinal Microglial Reactivity Contribute to Pain States in Collagen‐Induced Arthritis

OBJECTIVE: To evaluate the contribution of sensory neurons in ankle joints and adjacent tissue to the development of pain in collagen‐induced arthritis (CIA), and to determine the relationship between pain and the appearance of clinical signs. METHODS: Mechanical and heat hypersensitivity and hind p...

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Detalles Bibliográficos
Autores principales: Nieto, Francisco R., Clark, Anna K., Grist, John, Chapman, Victoria, Malcangio, Marzia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832255/
https://www.ncbi.nlm.nih.gov/pubmed/25707377
http://dx.doi.org/10.1002/art.39082