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Suppression of the noninvolved pair of the myeloma isotype correlates with poor survival in newly diagnosed and relapsed/refractory patients with myeloma

Heavy light chain (HLC) assays allow precise measurement of the monoclonal and of the noninvolved polyclonal immunoglobulins of the same isotype as the M‐protein (e.g., monoclonal IgAκ and polyclonal IgAλ in case of an IgAκ myeloma), which was not possible before. The noninvolved polyclonal immunogl...

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Detalles Bibliográficos
Autores principales: Ludwig, Heinz, Milosavljevic, Dejan, Berlanga, Oscar, Zojer, Niklas, Hübl, Wolfgang, Fritz, Veronique, Harding, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832268/
https://www.ncbi.nlm.nih.gov/pubmed/26662888
http://dx.doi.org/10.1002/ajh.24268