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Incorporating Functional Genomic Information in Genetic Association Studies Using an Empirical Bayes Approach
There is a large amount of functional genetic data available, which can be used to inform fine‐mapping association studies (in diseases with well‐characterised disease pathways). Single nucleotide polymorphism (SNP) prioritization via Bayes factors is attractive because prior information can inform...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832271/ https://www.ncbi.nlm.nih.gov/pubmed/26833494 http://dx.doi.org/10.1002/gepi.21956 |